Pandey, J.K. (2012) Biomarkers: A Potential Prognostic tool for Silicosis. Indian Journal of Occupational and Environmental Medicine, 16 (3). pp. 101-107.

PDF Restricted to Registered users only Download (137Kb) | Request a copy

Abstract

Long-term exposure to respirable dust containing silica leads to pneumoconiosis/silicosis. The disease is irreversible and incurable, and only preventive steps such as job rotation, use of personal protective equipment, etc., remain solutions to the problem. Under such a situation, early diagnosis or prediction may become very useful to control the disease. Biomarkers are biological parameters in blood serum that change their values with deposition of dust in the lung and onset of lung fibrosis. Since these biomarkers can help us to diagnose and in the prognosis of the disease before it is actually diagnosed by the conventional X-ray technique and lung function test used for diagnosis of silicosis. The present paper describes the various types of available biomarkers, their application and usefulness. The paper also suggests that further study of the behavior/level of these biomarkers on a specific subject with time may provide more useful information of a confirmatory nature for prevention of dust-linked diseases.

Item Type:	Article
Uncontrolled Keywords:	Biomarker, coal workers pneumoconiosis, silicosis
Subjects:	Non Coal Ventilation, Fire Gallery and Metallurgy
Divisions:	UNSPECIFIED
Depositing User:	Mr. B. R. Panduranga
Date Deposited:	30 Apr 2017 10:20
Last Modified:	30 Apr 2017 10:20
URI:	http://cimfr.csircentral.net/id/eprint/1665

Actions (login required)

View Item